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Study identifier: NCT05813964 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy, Acceptability and Safety of Event-driven HIV PrEP Using TAF/FTC in MSM in Thailand and France.

Condition: HIV/AIDS  ·  Sponsor: ANRS, Emerging Infectious Diseases

PhasePhase 3
Planned participants524
Who can joinMale, 18 Years to no upper limit
Healthy volunteersYes

About this study

The purpose of this study is to evaluate the efficacy, acceptability, and safety of a simplified event-driven pre-exposure prophylaxis of HIV based on oral TAF/FTC in HIV-uninfected cisgender men who have sex with men (MSM). Primary objective: To assess the efficacy of emtricitabine 200 mg + tenofovir alafenamide 25 mg (F/TAF), taken 2 to 24 hours before sexual intercourse followed by a second dose 24 hours after the first intake, in reducing the risk of HIV acquisition in MSM relative to the background HIV incidence rate.

This description comes directly from the study's public registry record.

Talk to the study team

Geoffroy LIEGEON, MD, PhD  ·  +33 142494991  ·  geoffroy.liegeon@aphp.fr

Gonzague JOURDAIN, MD, PhD  ·  : +66 8 1883 0065  ·  gonzague.jourdain@phpt.org

Always discuss trial participation with your own doctor first.

Locations (4)

AP-HP - Hospital LariboisièreParis, FranceRecruiting
AP-HP - Hôpital Saint-LouisParis, FranceRecruiting
MPlus ClinicChiang Mai, ThailandRecruiting
STIs Clinic of the Office of Disease Prevention and Control Region 1Chiang Mai, ThailandRecruiting

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Source record: clinicaltrials.gov/study/NCT05813964