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Study identifier: NCT05813457 Synced from ClinicalTrials.gov · July 29, 2026
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Impact of an Early Identification Program for First-Episode Psychosis on the Duration of Untreated Psychosis

Condition: Psychotic Episode  ·  Sponsor: Centre Hospitalier Universitaire de Saint Etienne

PhaseNA
Planned participants416
Who can joinAll sexes, 15 Years to 35 Years
Healthy volunteersNo

About this study

The First-Episode Psychosis (FPE) is a severe disorder that can include delusions, cognitive disorders and suicidal behavior. In the majority of cases (more than 80%) it evolves into schizophrenia. Numerous studies show that the rapidity of the initial management of FPE would reduce the risk of negative evolution and would have a decisive impact on the short and long term prognosis. The rapidity of this management can be measured by the duration of untreated psychosis, or DUP (Duration of Untreated Psychosis), the time interval between the appearance of the first frank psychotic symptoms and the initiation of adequate psychiatric care. The objective of this study is to show the impact of an intervention facilitating access to specialized care for PEP on the reduction of DUP. This intervention consists of an early identification program for FPE, the PRESTO program, specifically targeting 3 determining steps in the reduction of DUP: * Informing the general population about psychotic disorders * Knowledge of front line actors (APL: general practitioners, school and university medicine, teenager's house, associative networks educators, emergency services, firefighters, etc.) about FPE and its management * Articulation between APL and specialized psychiatric care

This description comes directly from the study's public registry record.

Talk to the study team

Eric FAKRA, MD PhD  ·  (0)477127885  ·  eric.fakra@chu-st-etienne.fr

Amandine BAUDOT, CRA  ·  (0)477829450  ·  amandine.baudot@chu-st-etienne.fr

Always discuss trial participation with your own doctor first.

Locations (6)

Hospices Civils de LyonBron, FranceRecruiting
Chu Clermont-FerrandClermont-Ferrand, FranceRecruiting
Chu GrenobleGrenoble, FranceRecruiting
CHU de MontpellierMontpellier, FranceRecruiting
CHU de NîmesNîmes, FranceRecruiting
Chu Saint EtienneSaint-Etienne, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05813457