Condition: Anorexia Nervosa · Atypical Anorexia Nervosa (Other Specified Eating Disorder) · Bulimia Nervosa · Sponsor: Maastricht University
Amongst psychiatric illnesses, eating disorders (EDs) are notoriously difficult to treat and have a high mortality rate. The average duration of an ED is 6 years and for a majority of ED patients, the disorder will become chronic. Comorbid personality pathology such as negative core beliefs and early maladaptive schemas (EMS) are strongly related to ED severity and chronicity. Enhanced cognitive-behavioural therapy for eating disorders (CBT-E) is used as the first line transdiagnostic treatment for EDs. However, CBT-E is mainly symptom-focused and does not tap into these underlying core beliefs and EMS. Given the limited treatment effects of existing ED treatments, and the importance of comorbid personality pathology, there is an urgent need to examine more effective treatments for EDs. Group-schematherapy (GST) overcomes the limitations of CBT-E and preliminary results for treatment-resistant EDs are promising. However, robust evidence regarding the clinical and cost-effectiveness of GST for patients that do not benefit from CBT-E is not yet available. The central aim of this project is to investigate the clinical and cost-effectiveness of GST for EDs in patients with comorbid personality pathology, who do not show a clinically significant response in the first phase of CBT-E. This is relevant and important as studies examining the effectiveness of GST for EDs are scarce. This project is a joint research initiative of three academic centers (Dutch Universities), four large …
This description comes directly from the study's public registry record.
Jeffrey Roelofs, Dr. · +31433881607 · j . roelofs @ maastricht university . nl
Suzanne Mares, Dr. · +31688 933 5701 · s.mares@ggnet.nl
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| GGz Breburg | Breda, Netherlands | Recruiting |
| Accare | Groningen, Netherlands | Recruiting |
| GGZ Friesland | Leeuwarden, Netherlands | Recruiting |
| GGNet Amarum | Nijmegen, Netherlands | Recruiting |
| GGz Breburg | Tilburg, Netherlands | Recruiting |
| Co-eur | Utrecht, Netherlands | Recruiting |
| GGNet Amarum | Warnsveld, Netherlands | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05812950