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Study identifier: NCT05810402 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Liver Cancer and Immunotherapy in the Liquid Biopsy Era

Condition: Hepatocellular Carcinoma · BCLC Stage B Hepatocellular Carcinoma · BCLC Stage C Hepatocellular Carcinoma  ·  Sponsor: University Hospital, Montpellier

PhaseNA
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The goal of this prospective clinical trial is to identify a predictive biomarker in patients with advanced HCC (stage B and C) using a combinatorial approach of the liquid biopsy. The main questions it aims to answer are: * Is multi-omic liquid biopsy approach able to identify a strong predictive biomarker of immunotherapy efficiency? * Is there a correlation between tissue biopsy (PD-L1 tissue level of expression) and liquid biopsy (detection of CTC expressing PD-L1) in HCC patients? Participants blood will be collected at several time points.

This description comes directly from the study's public registry record.

Talk to the study team

Thomas Bardol, M.D.  ·  +33682882757  ·  t-bardol@chu-montpellier.fr

Catherine Guillemare  ·  +33467332304  ·  c-guillemare@chu-montpellier.fr

Always discuss trial participation with your own doctor first.

Locations (1)

CHU MontpellierMontpellier, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05810402