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Study identifier: NCT05806515 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

Condition: Prostate Adenocarcinoma · Stage IIIB Prostate Cancer AJCC v8 · Stage IIIC Prostate Cancer AJCC v8  ·  Sponsor: SWOG Cancer Research Network

PhasePhase 2
Planned participants44
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II trial tests how well carboplatin before surgery works in treating patients with high-risk prostate cancer and an inherited BRCA1 or BRCA2 gene mutation. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping, or slowing the growth of tumor cells. Giving carboplatin before surgery may shrink tumors in patients with high-risk prostate cancer with BRCA1 and BRCA2 gene mutations.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (133)

Anchorage Associates in Radiation MedicineAnchorage, Alaska, United StatesRecruiting
Anchorage Radiation Therapy CenterAnchorage, Alaska, United StatesRecruiting
Alaska Breast Care and Surgery LLCAnchorage, Alaska, United StatesRecruiting
Alaska Oncology and Hematology LLCAnchorage, Alaska, United StatesRecruiting
Alaska Women's Cancer CareAnchorage, Alaska, United StatesRecruiting
Anchorage Oncology CentreAnchorage, Alaska, United StatesRecruiting
Katmai Oncology GroupAnchorage, Alaska, United StatesRecruiting
Providence Alaska Medical CenterAnchorage, Alaska, United StatesRecruiting
Cancer Center at Saint Joseph'sPhoenix, Arizona, United StatesRecruiting
Mission Hope Medical Oncology - Arroyo GrandeArroyo Grande, California, United StatesRecruiting
Providence Saint Joseph Medical Center/Disney Family Cancer CenterBurbank, California, United StatesRecruiting
Mercy Cancer Center �� CarmichaelCarmichael, California, United StatesRecruiting

+ 121 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05806515