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Study identifier: NCT05805436 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Preop Laxatives in Robotic Urologic Surgery

Condition: Prostate Cancer · Kidney Cancer · Constipation  ·  Sponsor: Chad R. Tracy

PhasePhase 4
Planned participants240
Who can joinAll sexes, 30 Years to 100 Years
Healthy volunteersYes

About this study

Minimally-invasive surgery, either laparoscopic or robotic, is commonly used in urology. Several urologic procedures including prostatectomy, radical nephrectomy, and partial nephrectomy are now commonly performed robotically. Patients undergoing these procedures often have delayed return of bowel function and persistent gastrointestinal symptoms including nausea/vomiting, abdominal distension, and bloating for several days to weeks after surgery. Postoperative stool softeners and laxatives are routinely used in an effort to minimize these symptoms, with varying degrees of success. The aim of this study will be to evaluate whether the use of a preoperative osmotic laxative will be beneficial in improving recovery of bowel function and alleviating postoperative gastrointestinal complaints in patients undergoing these procedures. Patients will be randomized to either receive or not receive three days of polyethylene glycol (PEG, also known as MiraLAX) on the three days before surgery. Patients in both groups will receive the same postoperative bowel regimen including scheduled PEG both in the hospital and upon discharge until first bowel movement. Patients will be given a questionnaire and diary to record their postoperative gastrointestinal symptoms and time to first bowel movement. These questionnaires and diaries will then be analyzed to determine differences in time to first bowel movement and gastrointestinal complaints during their recovery from surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Chad Tracy, MD  ·  +1 319 335 8056  ·  chad-tracy@uiowa.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Iowa Hospitals & ClinicsIowa City, Iowa, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05805436