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Study identifier: NCT05802121 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Akkermansia Muciniphilia and Metabolic Side Effects of ADT

Condition: Prostate Cancer · Metabolic Syndrome · Obesity  ·  Sponsor: Western University

PhaseEARLY_Phase 1
Planned participants30
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The overriding objectives of this study are: 1. Primary outcomes: 1. To confirm that administration of oral acetate increases the proportion of A. muciniphilia in the stool samples of patients with metastatic, castration-sensitive prostate cancer compared to a standard of care arm. 2. To confirm tolerability and assess for side effects of oral acetate supplementation. 2. Secondary outcomes: 1. To determine if increased counts of A. muciniphilia correlate with improved metabolic parameters and improved bone health.

This description comes directly from the study's public registry record.

Talk to the study team

Kaydee Connors  ·  519-685-8500  ·  kaydee.connors@lhsc.on.ca

Stephen Mardell  ·  519-685-8500  ·  stephen.mardell@lhsc.on.ca

Always discuss trial participation with your own doctor first.

Locations (1)

London Health Sciences Centre - Victoria HospitalLondon, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05802121