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Study identifier: NCT05800223 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Armatinib Alone or in Combination With SRT for Brain Metastases EGFR-mutated Non-small Cell Lung Cancer

Condition: Non-small Cell Lung Cancer Metastatic  ·  Sponsor: Shanghai Cancer Hospital, China

PhasePhase 3
Planned participants300
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Objective:Patients with asymptomatic or minimally symptomatic Stage IV EGFR-positive NSCLC with baseline intracranial metastases. Aim: To investigate the timing, efficacy and safety of radiotherapy in patients with EGFR positive brain metastases treated with armatinib alone or combined with stereotactic radiotherapy. Method: Almonertinib: specification 55mg/tablet; The dosage is 110 mg / day (2 tablets / day) orally once a day; SBRT: 3-5 doses of 27-40 Gy

This description comes directly from the study's public registry record.

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Locations (1)

Fudan University Shanghai Cancer CenterShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05800223