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Study identifier: NCT05800210 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases

Condition: Acute Lymphoblastic Leukemia · Acute Myeloid Leukemia · Juvenile Myelomonocytic Leukemia  ·  Sponsor: University of Florida

PhasePhase 2
Planned participants20
Who can joinAll sexes, 6 Months to 39 Years
Healthy volunteersNo

About this study

This study will assess the safety, efficacy, and feasibility of ⍺/β CD3+ T-cell and CD19+ B-cell depletion in allogeneic stem cell transplantation in patients with acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML), juvenile myelomonocytic leukemia (JMML), high risk myelodysplastic syndrome (MDS), chronic myeloid leukemia (CML) and lymphoma. Subjects will receive an allogeneic stem cell transplant that has been depleted of ⍺/β CD3+ T-cells and CD19+ B-cells using the Miltenyi CliniMACS Prodigy® system.

This description comes directly from the study's public registry record.

Talk to the study team

Beate Greer  ·  352-294-8744  ·  bgreer01@ufl.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of FloridaGainesville, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05800210