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Study identifier: NCT05797168 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

Condition: Ovarian Cancer · Lung Adenocarcinoma · Endometrial Cancer  ·  Sponsor: AstraZeneca

PhasePhase 1/Phase 2
Planned participants602
Who can joinAll sexes, 18 Years to 130 Years
Healthy volunteersNo

About this study

This research is designed to determine if experimental treatment with Antibody-drug conjugate, AZD5335, alone, or in combination with anti-cancer agents is safe, tolerable, and has anti-cancer activity in patients with advanced tumors

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (60)

Research SiteDuarte, California, United StatesRecruiting
Research SiteIrvine, California, United StatesRecruiting
Research SiteLa Jolla, California, United StatesWithdrawn
Research SiteAurora, Colorado, United StatesRecruiting
Research SiteLouisville, Kentucky, United StatesTerminated
Research SiteBoston, Massachusetts, United StatesRecruiting
Research SiteDetroit, Michigan, United StatesRecruiting
Research SiteColumbus, Ohio, United StatesRecruiting
Research SitePortland, Oregon, United StatesRecruiting
Research SiteProvidence, Rhode Island, United StatesRecruiting
Research SiteProvidence, Rhode Island, United StatesWithdrawn
Research SiteHouston, Texas, United StatesRecruiting

+ 48 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05797168