Condition: Medication-related Osteonecrosis of the Jaw (MRONJ) · Sponsor: University Hospital, Limoges
Medication-related osteonecrosis of the jaw (MRONJ) occurs after taking bisphosphonates or targeted therapies. It leads to a significant decrease in quality of life with pain, eating and chewing disorders, and malnutrition. Current treatments are only partially effective. PENTO (pentoxifylline and tocopherol) has been shown to be effective in maxillary osteoradionecrosis. The objective of this study is to evaluate the proportion of bone recovery in patients receiving PENTO in MRONJ at 12 months.
This description comes directly from the study's public registry record.
Julie USSEGLIO, Dr · +33 (0) 555 056 120 · julie.usseglio@chu-limoges.fr
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| Limoges university hospital | Limoges, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05795647