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Study identifier: NCT05793151 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy

Condition: Head and Neck Cancer · Head and Neck Squamous Cell Carcinoma · Oropharynx Cancer  ·  Sponsor: Medical University of South Carolina

PhaseNA
Planned participants532
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to compare the effectiveness of a navigation-based multilevel intervention (ENDURE) with treatment as usual (TAU) to improve the initiation of guideline-adherent postoperative radiation therapy among patients with head and neck cancer. The main questions the trial aims to answer are: 1. Does ENDURE improve initiation of timely PORT relative to treatment as usual? 2. What are the mechanisms through which ENDURE improves timeliness to treatment? 3. What are the barriers and facilitators to the implementation of ENDURE into routine clinical care?

This description comes directly from the study's public registry record.

Talk to the study team

Evan M Graboyes, MD, MPH  ·  843-792-0719  ·  graboyes@musc.edu

Always discuss trial participation with your own doctor first.

Locations (4)

Washington University in St. LouisSt Louis, Missouri, United StatesRecruiting
Duke University Medical CenterDurham, North Carolina, United StatesRecruiting
Medical University of South CarolinaCharleston, South Carolina, United StatesRecruiting
Baylor College of MedicineHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05793151