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Study identifier: NCT05792722 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Evaluating Safety and Efficacy of Prostate-sparing Radical Cystectomy

Condition: Bladder Cancer  ·  Sponsor: Johns Hopkins University

PhaseNA
Planned participants70
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this clinical trial is to determine if prostate-capsule-sparing cystectomy improves functional outcomes without comprising oncologic outcomes in male patients receiving a radical cystectomy. Patients will be randomized to one of two groups: prostate capsule-sparing radical cystectomy or nerve-sparing radical cystectomy. Patients will be monitored following standard of care guidelines and clinical data will be collected. Patients in both groups will be asked to complete an erectile function questionnaire at multiple timepoints. Patients who receive an orthotopic neobladder will be asked to complete a questionnaire to monitor urinary function at multiple timepoints. Patient adverse events will be monitored to ensure patients safety.

This description comes directly from the study's public registry record.

Talk to the study team

Armine Smith, MD  ·  202-660-5561  ·  asmit165@jhmi.edu

Domani Rodriguez  ·  drodri59@jh.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Sibley Memorial HospitalWashington D.C., District of Columbia, United StatesRecruiting
Johns Hopkins HospitalBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05792722