Condition: Female Breast Cancer · Sponsor: West German Study Group
There is only limited data for premenopausal patients in general, as well as for differences in the use of OFS in the subgroups of pre- and perimenopausal patients, respectively. The WSG ADAPT trial data on the impact of postmenopausal status and/or use of OFS within 3-4 weeks endocrine induction therapy show relevant impact of OFS/postmenopausal status on Ki-67 response; also, secondary amenorrhea after (neo-)adjuvant chemotherapy was a positive predictor of outcome due to OFS \[8, 9\]. This registry will give insights in the real-world use of OFS and the effect of secondary amenorrhea in female pre- and perimenopausal patients with or without previous use of chemotherapy and with different endocrine treatments (ET +/- GnRH). As adherence over time (5-10 years) plays a major role in the endocrine treatment, the registry will follow patients' treatments for up to 10 years and include QoL information. Results of MammaPrint® (MammaPrint® Index) as indicating factor for chemotherapy use and risk classification, thus, choice of adjuvant treatment (chemotherapy, OFS combined with endocrine therapy, or endocrine therapy alone) will be correlated to outcome under real-world conditions. Baseline, treatment, and relapse data shall be collected to gain further insight in the treatment paths, treatment adherence, and outcome of such patients.
This description comes directly from the study's public registry record.
Julian Moellers · 00492161566 23-0 · julian.moellers@wsg-online.com
Anja Braschoss, MD · 04917682119153 · anja.braschoss@wsg-online.com
Always discuss trial participation with your own doctor first.
| Klinikum-Mittelbaden GmbH, Studienzentrale/Brustzentrum | Baden-Baden, Baden-Wurttemberg, Germany | Recruiting |
| Helios Klinikum Pforzheim, Brustzentrum | Pforzheim, Baden-Wurttemberg, Germany | Recruiting |
| Diakonieklinikum Stuttgart, Brustzetrum | Stuttgart, Baden-Wurttemberg, Germany | Active Not Recruiting |
| Universitätsfrauenklinik Ulm - Frauenheilkunde und Geburtshilfe | Ulm, Baden-Wurttemberg, Germany | Recruiting |
| GRN Klinik Weinheim/ Gynäkologie/Brustzentrum | Weinheim, Baden-Wurttemberg, Germany | Recruiting |
| ViDia Christliche Kliniken Karlsruhe | Karlsruhe, Baden-Wüttemberg, Germany | Recruiting |
| Studienzentrum Onkologie Ravensburg | Ravensburg, Baden-Wüttemberg, Germany | Recruiting |
| Klinikum St. Marien Amberg | Amberg, Bavaria, Germany | Recruiting |
| HOP Gemeinschaftspraxis Dres. Heinrich/Bangerter, Augsburg | Augsburg, Bavaria, Germany | Recruiting |
| Universitätsklinikum Augsburg, Brustzentrum | Augsburg, Bavaria, Germany | Recruiting |
| Medias Klinikum | Burghausen, Bavaria, Germany | Active Not Recruiting |
| Klinikum Fürstenfeldbruck, Westdeutsches Brust- Centrum | Fürstenfeldbruck, Bavaria, Germany | Recruiting |
+ 59 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT05792150