● Recruiting

Venetoclax Treatment (26 Cycles) With 6 Cycles or 12 Cycles of Epcoritamab in Patients With Relapsed or Refractory CLL or SLL

Condition: CLL/SLL · Sponsor: Stichting Hemato-Oncologie voor Volwassenen Nederland

PhasePhase 1/Phase 2

Planned participants112

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

In this study, efficacy and safety of 2 regimens that combine the CD3-CD20 T cell engager epcoritamab with venetoclax will be tested in relapsed/refractory CLL and SLL patients. The trial starts with phase I part to establish the recommended dose level (RDL) of epcoritamab in the combination with venetoclax for the phase II trial.

This description comes directly from the study's public registry record.

Talk to the study team

Arnon Kater · +31 6-11491753 · a.p.kater@amsterdamumc.nl

Mark-David Levin · m-d.levin@asz.nl

Always discuss trial participation with your own doctor first.

Locations (24)

BE-Antwerpen-ZNASTUIVENBERG	Antwerp, Belgium	Not Yet Recruiting
BE-Roeselare-AZDELTA	Roeselare, Belgium	Not Yet Recruiting
DK-Aalborg-ALBOGUH	Aalborg, Denmark	Not Yet Recruiting
DK-Copenhagen-RIGSHOSPITALET	Copenhagen, Denmark	Recruiting
DK-Odense-OUH	Odense, Denmark	Not Yet Recruiting
DE-Berlin-HELIOSBERLINBUCH	Berlin, Germany	Not Yet Recruiting
DE-Köln-UKKOELN	Cologne, Germany	Not Yet Recruiting
DE-Freiburg-UNIKLINIKFREIBURG	Freiburg im Breisgau, Germany	Not Yet Recruiting
DE-Greifswald-UNIGREIFSWALD	Greifswald, Germany	Not Yet Recruiting
DE-Munster-GEMEINSCHAFTSPRAXIS	Münster, Germany	Not Yet Recruiting
DE-Stuttgart-RBK	Stuttgart, Germany	Not Yet Recruiting
DE-Ulm-UNIKLINKULM	Ulm, Germany	Not Yet Recruiting

+ 12 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05791409