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Study identifier: NCT05789667 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Gender-based Impact on Safety and Efficacy of Lenvatinib in Patients With Differentiated Thyroid Cancer

Condition: Differentiated Thyroid Cancer · Gender  ·  Sponsor: Regina Elena Cancer Institute

PhaseN/A
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Lenvatinib is approved for the treatment of radioiodine refractory differentiated thyroid cancer. Despite gender can play a crucial role un in safety and efficacy of oncological product, little is know on gender difference in lenvatinb effacacy and safety in the context of radioiodine refractory differentiated thyroid cancer. The primary objective of the study is to assess safety and toxicity profile in male and female patients in terms of dose reduction. The secondary objectives are to assess sex and gender difference in: the number and the incidence of adverse events; response rate according to RECIST criteria 1.1; progression free survival, overall survival and duration of response.

This description comes directly from the study's public registry record.

Talk to the study team

Marialuisa Appetecchia, Prof  ·  00390652666026  ·  marialuisa.appetecchia@ifo.it

Always discuss trial participation with your own doctor first.

Locations (1)

Regina Elena National Cancer InstituteRome, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT05789667