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Study identifier: NCT05786742 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Ultra Hypofractionnated Radiotherapy With HDR Brachytherapy Boost.

Condition: Prostate Cancer · Radiotherapy Side Effect · Hypofractionation  ·  Sponsor: CHU de Quebec-Universite Laval

PhaseNA
Planned participants205
Who can joinMale, 18 Years to 95 Years
Healthy volunteersYes

About this study

Phase 1-2 study, comparing ultra-hypofractionnated (UH) to a moderately hypofractionnated (MH) radiation therapy, with image guided HDR prostate brachytherapy. Using iso-equivalent doses, a non-inferiority analysis will be done in order to prove UH non-inferior to MH, toxicity wise. Acceptability, tolerability, acute and late toxicity will be reported. MRI visible dominant intra-prostatic lesion will be outlines and variability between radiation oncologists and radiologists will be reported. As secondary objective, biochemical and clinical failure free survival will be reported at 5 \& 10 years.

This description comes directly from the study's public registry record.

Talk to the study team

Andre-Guy Martin  ·  14186915264  ·  andre-guy.martin.med@ssss.gouv.qc.ca

Josee Allard  ·  14186915264  ·  josee.allard@chudequebec.ca

Always discuss trial participation with your own doctor first.

Locations (1)

CHUdeQuebecQuébec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05786742