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Study identifier: NCT05783505 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Multicomponent Intervention Program to Prevent and Reduce ICU Agitation and Physical Restraint Use

Condition: Agitation,Psychomotor  ·  Sponsor: Radboud University Medical Center

PhaseNA
Planned participants480
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Despite deleterious effects, physical restraints are still commonly used in (expected to become) agitated patients in Dutch ICUs (20-25%). This study aims to determine the effectiveness of a person-centered multicomponent intervention (MCI) program consisting of non-pharmacological interventions combined with goal directed light sedation using dexmedetomidine compared to the old standard of care including physical restraints in (expected to become) agitated adult ICU patients.

This description comes directly from the study's public registry record.

Talk to the study team

Rens Kooken, MSc  ·  +31 24 361 6735  ·  rens.kooken@radboudumc.nl

Bram Tilburgs, PhD  ·  +31 24 361 4996  ·  bram.tilburgs@radboudumc.nl

Always discuss trial participation with your own doctor first.

Locations (5)

Noordwest ZiekenhuisgroepAlkmaar, NetherlandsRecruiting
Bravis ZiekenhuisBergen op Zoom, NetherlandsRecruiting
Amphia ZiekenhuisBreda, NetherlandsRecruiting
Elkerliek ZiekenhuisHelmond, NetherlandsRecruiting
VieCuri Medisch CentrumVenlo, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT05783505