Condition: Stress · Sponsor: Centre Hospitalier Universitaire de Nice
Patient undergoing surgery is exposed to many stressors: diachronic (gesture anticipation), synchronic (intraoperative aggression) and historical (subject's personality). Reducing the level of stress experienced is a factor for improving the quality of the surgical gesture and the simplicity of the follow-up. The previous methods used were intended to reduce the body's reactivity to aggressions through anaesthesia consultation and L-Tyrosine supplementation. Currently with the progression of outpatient surgery and the need for early rehabilitation, L-Tyrosine supplementation is suppressed to improve recovery. Some patients, however, have a high level of stress that may require anxiolysis when the ideal treatment does not exist (ineffective hydroxyzine, benzodiazepines having many side effects). The strategy of this work is to improve the body's ability to respond to stressors, by administering l-tyrosine with no impact on waking or returning home.
This description comes directly from the study's public registry record.
Bertrand PRUNET, PU-PH · +377 97 98 98 19 · bertrand.prunet@chpg.mc
Nicolas RIJO · +377 97 98 84 45 · nicolas.rijo@chpg.mc
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Source record: clinicaltrials.gov/study/NCT05782829