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Study identifier: NCT05782335 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Analysis of T and B Cell Repertoire Changes in Response to Orencia® (Abatacept) in Rheumatoid Arthritis

Condition: Rheumatoid Arthritis  ·  Sponsor: Hospital for Special Surgery, New York

PhaseN/A
Planned participants72
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The condition that will be studied is Rheumatoid Arthritis (RA), and in particular, RA patients with moderate to highly active disease who were prescribed Abatacept (Orencia®) (ABA) by their physician during their setting of care at Hospital for Special Surgery (HSS). This investigator-initiated, prospective, comparative, 3-arm observational study will examine changes in lymphocytes in RA patients starting abatacept compared to RA patients starting TNF inhibitors and to healthy controls. This will help investigators to learn more about the processes that cause joints to swell and hurt. This may also offer clues that might predict which patients will have a good or poor response to these treatments.

This description comes directly from the study's public registry record.

Talk to the study team

Margaret Butler, BS  ·  917-260-4906  ·  ButlerM@hss.edu

Caroline Reidy, MPH  ·  646-704-3426  ·  ReidyC@hss.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Hospital for Special SurgeryNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05782335