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Study identifier: NCT05774951 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Camizestrant in ER+/HER2- Early Breast Cancer After at Least 2 Years of Standard Adjuvant Endocrine Therapy

Condition: Breast Cancer, Early Breast Cancer  ·  Sponsor: AstraZeneca

PhasePhase 3
Planned participants4300
Who can joinAll sexes, 18 Years to 130 Years
Healthy volunteersNo

About this study

This is a Phase III open-label study to assess if camizestrant improves outcomes compared to standard endocrine therapy in patients with ER+/HER2 - early breast cancer with intermediate or high risk for disease recurrence who completed definitive locoregional therapy (with or without chemotherapy) and standard adjuvant endocrine therapy (ET) for at least 2 years and up to 5 years. The planned duration of treatment in either arm of the study is 60 months.

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

AstraZeneca Breast Cancer Study Locator Service  ·  1-877-400-4655  ·  az-bcsl@careboxhealth.com

Always discuss trial participation with your own doctor first.

Locations (709)

Research SiteBirmingham, Alabama, United StatesActive Not Recruiting
Research SiteDothan, Alabama, United StatesActive Not Recruiting
Research SiteAnchorage, Alaska, United StatesActive Not Recruiting
Research SiteChandler, Arizona, United StatesActive Not Recruiting
Research SiteHot Springs, Arkansas, United StatesActive Not Recruiting
Research SiteAnaheim, California, United StatesActive Not Recruiting
Research SiteBeverly Hills, California, United StatesActive Not Recruiting
Research SiteConcord, California, United StatesActive Not Recruiting
Research SiteCorona, California, United StatesActive Not Recruiting
Research SiteFountain Valley, California, United StatesActive Not Recruiting
Research SiteGreenbrae, California, United StatesActive Not Recruiting
Research SiteLos Alamitos, California, United StatesActive Not Recruiting

+ 697 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05774951