Condition: Adenoid Cystic Carcinoma · Metastatic Adenoid Cystic Carcinoma · Recurrent Adenoid Cystic Carcinoma · Sponsor: Glenn J. Hanna
The goal of this study is to treat patients with NOTCH active advanced adenoid cystic carcinoma (ACC) tumors with a combination or two different oral medications to slow tumor growth and improve survival outcomes. The names of the study drugs involved in this study are: * CB-103 (an oral NOTCH pathway inhibitor) * Abemaciclib (CDK4/6 inhibitor) * Lenvatinib (a vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor (TKI))
This description comes directly from the study's public registry record.
Glenn Hanna, MD · 617-632-3090 · Gjhanna@partners.org
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| Dana Farber Cancer Institute | Boston, Massachusetts, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05774899