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Study identifier: NCT05774860 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neural Bases of Social Cognitive Processing in Healthy Individuals

Condition: Healthy Volunteers  ·  Sponsor: Istituti Clinici Scientifici Maugeri SpA

PhaseN/A
Planned participants200
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersNo

About this study

The goal of this single center non-interventional fMRI and EEG study is to assess the neural bases of social cognitive processing in healthy individuals, and whether/how their responsiveness is modulated by ageing. The main questions it aims to answer are: * are there specific brain regions where individual differences in social cognitive performance reflect well-established metrics of social cogntion such as empathy and mentalizing? * is there a relationship, at the behavioral and neural levels, between ageing-related changes in social cognitive performance and empathy/mentalizing? Healthy participants will be recruited for: * a behavioral assessment including multiple tests of social cognition focused on empathy and mentalizing; * for half participants: a fMRI session to collect data concerning a) brain activity associated with action observation and social cognitive processing, b) brain structural morphometriy (grey-matter volume/density), and c) brain structural connectivity (diffusion weighted imaging) * for half participants: a EEG session to collect data concerning brain responsiveness to social cognitive processing with higher temporal resolution than that afforded by fMRI. Results will provide an useful baseline for investigating alterations of social cognitive processing, and of their neural bases, in pathological conditions.

This description comes directly from the study's public registry record.

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Locations (1)

Istituti Clinici Scientifici Maugeri SpAPavia, Ita, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT05774860