● Recruiting

Trial Of PreoperAtive Radiation (TOPAz): A Randomized Trial Comparing Hypofractionated Versus Conventionally Fractionated Preoperative Radiation Followed by Mastectomy With Immediate Autologous Breast Reconstruction With Integrated Nanomechanical Biomarker Evaluation

Condition: Breast Cancer · Sponsor: M.D. Anderson Cancer Center

PhasePhase 3

Planned participants126

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

To compare the outcomes of and responses to 2 different radiation therapy schedules (the standard radiation amount and number of doses versus less radiation and fewer doses) that are being given before having breast cancer surgery (cancer removal and reconstruction).

This description comes directly from the study's public registry record.

Talk to the study team

Benjamin D. Smith, MD · (713) 563-2380 · bsmith3@mdanderson.org

Always discuss trial participation with your own doctor first.

Locations (1)

M D Anderson Cancer Center

Houston, Texas, United States

Recruiting

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Source record: clinicaltrials.gov/study/NCT05774678