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Study identifier: NCT05772923 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Organ Preservation in Rectal Cancer: Contact X-ray Brachytherapy vs Extending the Waiting Interval and Local Excision

Condition: Organ Preservation · Rectal Cancer · Quality of Life  ·  Sponsor: The Netherlands Cancer Institute

PhaseNA
Planned participants168
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this prospective phase II feasibility study is to evaluate two additional local treatment options in rectal cancer patients with a good clinical response after neoadjuvant (chemo)radiation: contact x-ray brachytherapy versus extension of the waiting interval with or without local excision, and to investigate which rate of organ preservation can be achieved.

This description comes directly from the study's public registry record.

Talk to the study team

Barbara M Geubels, MD  ·  0205129001  ·  b.geubels@nki.nl

Brechtje A Grotenhuis, MD, PhD  ·  020 239 9111  ·  b.grotenhuis@nki.nl

Always discuss trial participation with your own doctor first.

Locations (7)

Radbouw University Medical CentreNijmegen, Gelderland, NetherlandsRecruiting
Catharina HospitalEindhoven, North Brabant, NetherlandsRecruiting
Antoni van LeeuwenhoekAmsterdam, North Holland, NetherlandsRecruiting
Deventer HospitalDeventer, Overijssel, NetherlandsRecruiting
IsalaZwolle, Overijssel, NetherlandsRecruiting
Medical Center LeeuwardenLeeuwarden, Provincie Friesland, NetherlandsRecruiting
Ijsselland HospitalCapelle aan den IJssel, South Holland, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT05772923