Condition: Colorectal Cancer · Microsatellite Stable Colorectal Carcinoma · Sponsor: Fudan University
The goal of this clinical trial is to learn about efficacy of Vitamin E in combination with Fuquinitinib and Tirelizumab in patients with microsatellite stabilized mCRC who have failed standard therapy. The main question is to explore the survival time, safety and tolerability of the treatment. At the same time, the correlation between biomarkers (including PD-L1 expression, tumor mutation load, lymphocyte subpopulation, cytokines, TCR, intestinal microbes, and others) and the efficacy and drug resistance mechanism will be analyzed, so as to provide reference for the subsequent guidance of the screening of benefit groups.
This description comes directly from the study's public registry record.
Dawei Li, PhD · +8613774201693 · li_dawei@fudan.edu.cn
Zhiyu Chen, PhD · +8618721841159 · chanhj@aliyun.com
Always discuss trial participation with your own doctor first.
| 270 Dongan Road, Fudan University Shanghai Cancer Center | Shanghai, Shanghai Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05771181