Condition: Haematological Malignancy · Malignant Neoplasm · Lymphoproliferative Disorders · Sponsor: Cancer Research UK
This clinical trial is looking at a drug called alectinib. Alectinib is approved as standard of care treatment for adult patients with certain types of lung cancer. This means it has gone through clinical trials and been approved by the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK. Alectinib works in lung cancer patients with a particular mutation in their cancer known as ALK. Investigators now wish to find out if it will be useful in treating patients with other cancer types which have the same mutation. If the results are positive, the study team will work with the NHS and the Cancer Drugs Fund to see if these drugs can be routinely accessed for patients in the future. This trial is part of a trial programme called DETERMINE. The programme will also look at other anti-cancer drugs in the same way, through matching the drug to rare cancer types or ones with specific mutations.
This description comes directly from the study's public registry record.
Aida Sarmiento Castro · +44 207 242 0200 · determine@cancer.org.uk
Always discuss trial participation with your own doctor first.
| Belfast City Hospital | Belfast, United Kingdom | Recruiting |
| University Hospital Birmingham | Birmingham, United Kingdom | Recruiting |
| Birmingham Children's Hospital | Birmingham, United Kingdom | Not Yet Recruiting |
| Bristol Royal Hospital for Children | Bristol, United Kingdom | Recruiting |
| Bristol Haematology and Oncology Centre | Bristol, United Kingdom | Recruiting |
| Addenbrooke's Hospital | Cambridge, United Kingdom | Recruiting |
| Velindre Cancer Centre | Cardiff, United Kingdom | Recruiting |
| Cardiff Children's Hospital | Cardiff, United Kingdom | Not Yet Recruiting |
| Western General Hospital | Edinburgh, United Kingdom | Recruiting |
| The Beatson Hospital | Glasgow, United Kingdom | Recruiting |
| Royal Hospital for Children Glasgow | Glasgow, United Kingdom | Recruiting |
| Leicester Royal Infirmary | Leicester, United Kingdom | Recruiting |
+ 15 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05770037