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Study identifier: NCT05769140 Synced from ClinicalTrials.gov · July 29, 2026
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Measurement of Cardiopulmonary Variables After Acute Exposure to High Altitude

Condition: High Altitude Effects  ·  Sponsor: Centro Cardiologico Monzino

PhaseN/A
Planned participants8000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

As altitude increases, the availability of oxygen in the air decreases, and just to compensate for this lack, the body increases cardiac and respiratory work and changes blood pressure. But that is not all: at altitude the body's ability to use oxygen is also limited. Thus, there is on one hand less oxygen available, and on the other a lower capacity to use it. All this generates significant alterations at the cardiovascular level, to the point of running possible risks of heart attack, stroke and acute pulmonary edema, particularly for individuals already suffering from cardiovascular disease. The availability of modern cable cars allows an increasingly large number of individuals, including sedentary people, elderly subjects, and cardiorespiratory patients, to easily and rapidly reach high-altitude locations. Data on what happens on the cardiovascular system at high altitude are relatively scarce, and most experiments in the literature are limited by low sample sizes. The primary purpose of this study is to assess the characteristics of a large population that acutely reached high altitude at Punta Helbronner (3,466 m above sea level), a location on Mont Blanc that is readily accessible by a 20-minute cableway ride from Courmayeur (Entreves station, 1,300 m, Skyway Monte Bianco). We aim to create a unique database and study correlations between altitude and cardiorespiratory parameters (heart rate, blood pressure, and Hb saturation) by collecting medical history data and …

This description comes directly from the study's public registry record.

Talk to the study team

Piergiuseppe Agostoni, Prof  ·  +39 0258002772  ·  piergiuseppe.agostoni@ccfm.it

Always discuss trial participation with your own doctor first.

Locations (1)

Skyway Monte BiancoCourmayeur, Aosta, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT05769140