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Study identifier: NCT05769114 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Surgical Versus Non-Surgical Treatment of Thoracolumbar Burst Fracture

Condition: SPINAL Fracture · Burst Fracture · Spinal Instability of Thoracolumbar Region  ·  Sponsor: Insel Gruppe AG, University Hospital Bern

PhaseNA
Planned participants52
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

Treatment for acute traumatic thoracolumbar burst fractures differs significantly across the world in patients without neurological impairments and without damage to the posterior column of the spine. This randomized controlled, non-inferiority clinical trial's goal is to evaluate the effectiveness of surgery versus initial non-surgical treatment for patients with traumatic thoracolumbar spine burst fractures who don't have any neurological symptoms. The study's precise objectives are to: 1. evaluate the clinical outcome (Oswestry Disability Index) 2. evaluate the radiography result (restoration and maintenance of spinal alignment) 3. determine the prevalence of complications at least 24 months of follow-up of neurologically unaffected patients with acute traumatic burst fractures. Both groups will get the same therapy using standardized methods: The surgical group's entire patient population will get combined anterior-posterior (360°) spinal fusion therapy. Three-point hyperextension orthoses will be used to treat all patients in the non-surgical group for six weeks following the injury.

This description comes directly from the study's public registry record.

Talk to the study team

Christoph E Albers, PD Dr.  ·  +41 (0) 31 664 04 40  ·  christoph.albers@insel.ch

Sonja Häckel, Dr.  ·  +41 (0) 31 664 04 40  ·  sonja.haeckel@insel.ch

Always discuss trial participation with your own doctor first.

Locations (2)

InselspitalBern, SwitzerlandRecruiting
Ostschweizer Wirbelsaeulenzentrum Kantonsspital St. GallenSankt Gallen, SwitzerlandNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05769114