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Study identifier: NCT05763160 Synced from ClinicalTrials.gov · July 28, 2026
● Completed

An Open-label Study That Will Test a Second Treatment Session of RZL-012.

Condition: Submental Fat  ·  Sponsor: Raziel Therapeutics Ltd.

PhasePhase 2
Planned participants15
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

This is a Phase 2, open-label study in which subjects seeking further improvement of their SMF will be treated with a second treatment session of RZL-012. The second treatment session will be offered to subjects previously treated with RZL-012 under protocols RZL-012-SMF-SWMTG-P2US-001 or RZL-012-SMFC-P2US-001. Subjects who fully completed either of the trials and whose C-CAT score is 2, 3 or 4 will be eligible to participate in the new trial. For each subject, the study will consist of a screening period, baseline period in which subjects will receive a second treatment session of RZL-012 and a follow-up period. RZL-012 will be administered during a single treatment session via multiple injections into the submental area under the chin. Subjects will thereafter be monitored for safety and efficacy for at least 84 days.

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (1)

LuxurgeryManhattan, New York, United States

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Source record: clinicaltrials.gov/study/NCT05763160