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Study identifier: NCT05762952 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Dapagliflozin on Microvascular Function in Women With Symptoms of Coronary Artery Disease

Condition: Myocardial Ischemia  ·  Sponsor: University of Virginia

PhasePhase 1
Planned participants40
Who can joinFemale, 18 Years to 99 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to test the effects of a drug (in the drug class called sodium-glucose cotransporter 2 inhibitors) in women who have symptoms of ischemic heart disease. The main questions the study aims to answer are: Does blood flow in the heart improve with study drug? Participants will be randomly assigned to a 12-week course of the study drug, dapagliflozin 10mg, or placebo. Blood flow in the heart will be assessed using stress cardiac magnetic resonance imaging at baseline and 12 weeks. The researchers will compare the results from the two groups.

This description comes directly from the study's public registry record.

Talk to the study team

Caroline L Flournoy, PhD  ·  4349246104  ·  clf4w@uvahealth.org

Nicole J Sprouse, RN  ·  434-982-1058  ·  njb6m@uvahealth.org

Always discuss trial participation with your own doctor first.

Locations (1)

University of VirginiaCharlottesville, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05762952