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Study identifier: NCT05760287 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Echocardiographic Characterization of Cardiac Amyloidosis

Condition: Cardiac Amyloidosis  ·  Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

PhaseN/A
Planned participants255
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a mono-center observational ambispective study in which patients with cardiac amyloidosis evaluated at the Fondazione Policlinico Universitario Agostino Gemelli IRCCS (Rome, Italy) will be enrolled. The primary aim is to investigate echocardiographic findings, particularly using advanced echocardiographic techniques, such as two- and three-dimensional speckle-tracking analysis, that may be helpful in the differential diagnosis between cardiac amyloidosis and other cardiomyopathies with hypertrophic phenotype. Secondary aims are: 1) to evaluate the reversibility of myocardial damage, assessed by echocardiography, in response to a newly available specific treatment for patients with transthyretin-related cardiac amyloidosis (tafamidis) and its correlation with the clinical response 2) to investigate potential novel echocardiographic predictors of adverse cardiovascular outcomes.

This description comes directly from the study's public registry record.

Talk to the study team

Francesca Graziani, MD  ·  00390630154432  ·  francesca.graziani@policlinicogemelli.it

maria chiara meucci, MD  ·  00390630154432  ·  mariachiara.meucci@guest.policlinicogemelli.it

Always discuss trial participation with your own doctor first.

Locations (1)

Fondazione Policlinico Gemelli IRCCSRoma, RM, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT05760287