Condition: Multiple Sclerosis · Relapsing-remitting Multiple Sclerosis · Sponsor: Rennes University Hospital
The goal of this randomized clinical trial is to compare relapse remitting multiple sclerosis (RRMS) patients treated by ocrelizumab or by rituximab followed for 2 years. The main question it aims to answer is : • to demonstrate the non-inferiority of rituximab versus ocrelizumab in active relapsing MS patients on the % of patients without disease activity at 2 years. During the 2 years, the study includes 6 follow-up visits and the completion of various health and quality of life questionnaires. The protocol visits follow the usual schedule of treatment infusions for the disease (at initiation of treatment, 15 days after, and then every 6 months). Two comparison groups: Researchers will compare rituximab treated patients versus ocrelizumab treated patients to see the % of patients without disease activity at 2 years.
This description comes directly from the study's public registry record.
Laure MICHEL, MD · 0299286774 · laure.michel@chu-rennes.fr
Agnès Gazzola · 0299289194 · agnes.gazzola@chu-rennes.fr
Always discuss trial participation with your own doctor first.
| Hospices Civils de Lyon Hôpital Neurologique Pierre Wertheimer | Lyon, Bron, France | Not Yet Recruiting |
| CHRU de Brest - Hôpital la Cavale Blanche | Brest, France | Not Yet Recruiting |
| Centre Hospitalier Universitaire de Caen | Caen, France | Recruiting |
| Centre Hospitalier de Pontoise - GHT NOVO | Cergy-Pontoise, France | Not Yet Recruiting |
| Hôpital Gabriel Montpieds | Clermont-Ferrand, France | Not Yet Recruiting |
| Centre hospitalier de Gonnesse | Gonesse, France | Not Yet Recruiting |
| Groupe Hospitalier de l'Institut Catholique de Lille | Lille, France | Not Yet Recruiting |
| Centre Hospitalier Universitaire de Limoges | Limoges, France | Not Yet Recruiting |
| AP-HM - Hôpital la Timone | Marseille, France | Recruiting |
| CHRU de Montpellier - Hôpital Gui de Chauliac | Montpellier, France | Recruiting |
| Centre Hospitalier Régional de Nancy | Nancy, France | Recruiting |
| CHU de Nantes -Hôpital Nord Laennec | Nantes, France | Recruiting |
+ 11 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05758831