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Study identifier: NCT05758662 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Effect of Subclinical Leaflet Thrombosis and Prosthesis Type on Transcatheter Aortic Valve Degeneration (POPular PET TAVI)

Condition: Aortic Valve Stenosis  ·  Sponsor: St. Antonius Hospital

PhaseN/A
Planned participants180
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A multicentre cross-sectional cohort study to assess the difference in bioprosthetic micro-calcification activity, detected with 18F-NaF PET-CT, as early marker of transcatheter valve degeneration, between patients with vs. without subclinical leaflet thrombosis at five years after TAVI; and between patients with intra-annular vs. supra-annular TAVI prostheses.

This description comes directly from the study's public registry record.

Talk to the study team

Dirk-Jan van Ginkel, MD  ·  +31 (0)88 320 66 48  ·  d.van.ginkel@antoniusziekenhuis.nl

Prof. J.M. ten Berg, MD, PhD, MSc  ·  jurtenberg@gmail.com

Always discuss trial participation with your own doctor first.

Locations (4)

RigshospitaletCopenhagen, DenmarkRecruiting
St. Antonius HospitalNieuwegein, Utrecht, NetherlandsRecruiting
Amsterdam UMCAmsterdam, NetherlandsRecruiting
University of EdinburghEdinburgh, United KingdomNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05758662