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Study identifier: NCT05758077 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury

Condition: Acute Kidney Injury  ·  Sponsor: SeaStar Medical

PhaseNA
Planned participants339
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This randomized, controlled, pivotal study is intended to determine whether up to ten sequential 24-hour treatments with the Selective Cytopheretic Device (SCD) will improve survival in patients with Acute Kidney Injury (AKI) requiring continuous kidney replacement therapy (CKRT) when compared to CKRT alone (standard of care). This study is further intended to determine whether SCD therapy will reduce the duration of maintenance dialysis secondary to AKI. This study will enroll approximately 339 subjects across 30 US sites. Participants will be patients in an intensive care unit (ICU) setting with a diagnosis of AKI requiring CKRT.

This description comes directly from the study's public registry record.

Talk to the study team

Mohamed Zidan, MD  ·  844-427-8100  ·  mzidan@seastarmed.com

Kevin K Chung, MD  ·  844-427-8100  ·  kchung@seastarmed.com

Always discuss trial participation with your own doctor first.

Locations (38)

University of Alabama Birmingham HospitalBirmingham, Alabama, United StatesRecruiting
Mayo Clinic in ArizonaPhoenix, Arizona, United StatesNot Yet Recruiting
Ronald Reagan UCLA Medical CenterLos Angeles, California, United StatesRecruiting
Stanford UniversityPalo Alto, California, United StatesRecruiting
University of California San FranciscoSan Francisco, California, United StatesNot Yet Recruiting
University of Colorado Hospital Anschutz Medical CampusAurora, Colorado, United StatesWithdrawn
Mayo Clinic in FloridaJacksonville, Florida, United StatesNot Yet Recruiting
AdventHealth OrlandoOrlando, Florida, United StatesNot Yet Recruiting
Orlando Regional Medical CenterOrlando, Florida, United StatesWithdrawn
Emory HealthcareAtlanta, Georgia, United StatesNot Yet Recruiting
JMS Burn CenterAugusta, Georgia, United StatesWithdrawn
Northeast Georgia Health SystemGainesville, Georgia, United StatesNot Yet Recruiting

+ 26 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05758077