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Study identifier: NCT05757141 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

An Open-Label Exploratory Study of Fosigotifator in Participants With Vanishing White Matter Disease

Condition: Vanishing White Matter Disease  ·  Sponsor: Calico Life Sciences LLC

PhasePhase 1/Phase 2
Planned participants50
Who can joinAll sexes, 6 Months to no upper limit
Healthy volunteersNo

About this study

Fosigotifator is an investigational drug being researched for the treatment of Vanishing White Matter disease in adult, pediatric and infant participants. This is a 201-week, open-label, multiple cohort study enrolling adults, pediatric and infant participants with Vanishing White Matter disease. Participants will attend regular visits during the course of the study and complete medical assessments, blood tests, questionnaires, and be evaluated for side effects.

This description comes directly from the study's public registry record.

Talk to the study team

Call Center - English  ·  1-833-250-9660  ·  vwminfo@mylocalstudy.com

Always discuss trial participation with your own doctor first.

Locations (5)

Massachusetts General Hospital /ID# 270960Boston, Massachusetts, United StatesRecruiting
Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting
University of Utah /ID# 255624Salt Lake City, Utah, United StatesRecruiting
McGill University Health Centre - Glen SiteMontreal, Quebec, CanadaRecruiting
Amsterdam UMC, locatie VUmc /ID# 270955Amsterdam, North Holland, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT05757141