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Study identifier: NCT05755087 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Tegavivint for Treating Patients With Relapsed or Refractory Large B-Cell Lymphoma

Condition: Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type · Recurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type · Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements  ·  Sponsor: Lapo Alinari

PhasePhase 1
Planned participants18
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase I trial tests the safety, side effects, and best dose of tegavivint in treating patients with large b-cell lymphomas that has come back (relapsed) or does not respond to treatment (refractory). Tegavivint may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving tegavivint may help control the disease.

This description comes directly from the study's public registry record.

Talk to the study team

The Ohio State Comprehensive Cancer Center  ·  800-293-5066  ·  OSUCCCClinicaltrials@osumc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Ohio State University Comprehensive Cancer CenterColumbus, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05755087