Condition: Barretts Esophagus With Dysplasia · Barrett Esophagus · Esophageal Adenocarcinoma · Sponsor: University of Colorado, Denver
The purpose of this study is to learn the best approach to treating patients with known or suspected Barrett's esophagus by comparing endoscopic surveillance to endoscopic eradication therapy. To diagnose and manage Barrett's esophagus and low-grade dysplasia, doctors commonly use procedures called endoscopic surveillance and endoscopic eradication therapy. Endoscopic surveillance is a type of procedure where a physician will run a tube with a light and a camera on the end of it down the patients throat and remove a small piece of tissue. The piece of tissue, called a biopsy, is about the size of the tip of a ball-point pen and is checked for abnormal cells and cancer cells. Endoscopic eradication therapy is a kind of surgery which is performed to destroy the precancerous cells at the bottom of the esophagus, so that healthy cells can grow in their place. It involves procedures to either remove precancerous tissue or burn it. These procedures can have side effects, so it is not certain whether risking those side effects is worth the benefit people get from the treatments. While both of these procedures are widely accepted approaches to managing the condition, there is not enough research to show if one is better than the other. Barrett's esophagus and low-grade dysplasia does not always worsen to high-grade dysplasia and/or cancer. In fact, it usually does not. So, if a patient's dysplasia is not worsening, doctors would rather not put patients at risk unnecessarily. On t…
This description comes directly from the study's public registry record.
Jillian Welker · 2489127809 · jwelker89@gmail.com
Sandra Boimbo · 303-724-8892 · sandra.boimbo@cuanschutz.edu
Always discuss trial participation with your own doctor first.
| University of California, Los Angeles | Los Angeles, California, United States | Recruiting |
| Kaiser Permanente Oakland Medical Center | Oakland, California, United States | Recruiting |
| Kaiser Permanente | San Jose, California, United States | Recruiting |
| University of Colorado | Aurora, Colorado, United States | Recruiting |
| Florida Digestive Health Specialists | Sarasota, Florida, United States | Recruiting |
| Northwestern Memorial Hospital | Chicago, Illinois, United States | Recruiting |
| Indiana University Melvin & Bren Simon Cancer Center | Indianapolis, Indiana, United States | Recruiting |
| Johns Hopkins Universtiy | Baltimore, Maryland, United States | Recruiting |
| Beth Israel Deaconess Medical Center | Boston, Massachusetts, United States | Recruiting |
| University of Michigan | Ann Arbor, Michigan, United States | Recruiting |
| Washington University in St. Louis | St Louis, Missouri, United States | Recruiting |
| Dartmouth-Hitchcock Medical Center | Lebanon, New Hampshire, United States | Recruiting |
+ 11 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05753748