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Study identifier: NCT05752552 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study to Determine the Safety and Pharmacokinetics of DO-2 in Patients With Advanced or Refractory Solid Tumours

Condition: Adult Solid Tumor · Advanced Solid Tumor · Refractory Tumor  ·  Sponsor: DeuterOncology

PhasePhase 1
Planned participants55
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is a first-in-human, open-label, 2-part, Phase 1 dose escalation study of DO-2, administered orally to patients with advanced or refractory solid tumours, with MET aberrations, and no available, approved therapeutic alternative. The dose escalation is completed, Part 2 of the study is ongoing.

This description comes directly from the study's public registry record.

Talk to the study team

Timothy Perera, PhD  ·  +32473558353  ·  tperera@deuteroncology.com

Desirée Kanters  ·  dkanters@deuteroncology.com

Always discuss trial participation with your own doctor first.

Locations (13)

Institut Roi Albert II - UC LouvainBrussels, BelgiumRecruiting
UZAEdegem, BelgiumRecruiting
Universitair Ziekenhuis GentGhent, BelgiumRecruiting
UZ LeuvenLeuven, BelgiumRecruiting
Institut BergonieBordeaux, FranceRecruiting
Institut Cœur Poumon - CHU LilleLille, FranceRecruiting
Centre Léon BérardLyon, FranceRecruiting
Hôpitaux Universitaires de Marseille TimoneMarseille, FranceNot Yet Recruiting
Centre Antoine LacassagneNice, FranceNot Yet Recruiting
Centre Hospitalier Universitaire De RennesRennes, FranceRecruiting
Institut Gustave RoussyVillejuif, FranceNot Yet Recruiting
Radboud UMCNijmegen, NetherlandsRecruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05752552