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Study identifier: NCT05748197 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of ADCLEC.syn1 in People With Acute Myeloid Leukemia

Condition: Acute Myeloid Leukemia  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhasePhase 1
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to test the safety of ADCLEC.syn1 CAR T cells in people with relapsed or refractory AML. The researchers will try to find the highest dose of ADCLEC.syn1 CAR T cells that causes few or mild side effects in participants. Once the researchers find this dose, it will test it in a new group of participants to see if it is effective in treating their relapsed/refractory AML.

This description comes directly from the study's public registry record.

Talk to the study team

Jae Park, MD  ·  646-608-2091  ·  parkj6@mskcc.org

Mark Geyer, MD  ·  646-608-3745

Always discuss trial participation with your own doctor first.

Locations (7)

Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)Basking Ridge, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)Middletown, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Bergen (Limited Protocol Activities)Montvale, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Cancer Commack - Suffolk (Limited Protocol Activities)Commack, New York, United StatesRecruiting
Memorial Sloan Kettering Westchester (Limited Protocol Activities)Harrison, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Memorial Sloan Kettering Nassau (Limited Protocol Activities)Uniondale, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05748197