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Study identifier: NCT05746793 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

At High-risk for Pre-eclampsia After Assisted Reproductive Technology

Condition: Pre-Eclampsia  ·  Sponsor: CRG UZ Brussel

PhaseN/A
Planned participants1050
Who can joinFemale, 18 Years to 48 Years
Healthy volunteersYes

About this study

The overarching goal of the project is to unravel PE etiopathogenesis in high-risk patients (PCOS patients and oocyte acceptors) after assisted reproductive technology (ART) to individualize prenatal care following ART and to determine potential targets for new PE prevention options decreasing the morbidity/mortality caused by this pathology. More specifically, the following objectives/work packages (WPs) are put forward: * WP1 - PRECONCEPTION: Identify preconceptional maternal characteristics associated with in-creased risk of PE in ART patients (1a) and investigate the potential role of the endometrium prior to pregnancy (1b). * WP2 - DURING PREGNANCY: Evaluate the Fetal Medicine Foundation's (FMF) first trimester PE screening in selected high-risk groups post ART to explore the clinical benefit in this specific context (2a) and investigate the association between parameters during the pregnancy and PE development post-ART. * WP3 - AT DELIVERY: Identifying placental molecular pathways associated with PE post-ART.

This description comes directly from the study's public registry record.

Talk to the study team

Study nurses Brussels IVF  ·  +32 2 477 66 99  ·  studieverpleegkundigen_crg@uzbrussel.be

Always discuss trial participation with your own doctor first.

Locations (1)

Brussels IVFBrussels, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT05746793