Condition: Paroxysmal Nocturnal Hemoglobinuria · Sponsor: Regeneron Pharmaceuticals
This study is researching an experimental treatment combination with two experimental drugs called pozelimab and cemdisiran. The study is focused on people with paroxysmal nocturnal hemoglobinuria (PNH). The aim of this study is to see how safe and effective the pozelimab + cemdisiran combination is for people with PNH in the long term. The pozelimab + cemdisiran combination may be referred to as "study drugs" in this section. This study is looking at several other research questions, including: * How effective is the pozelimab + cemdisiran combination? * What side effects may happen from taking the study drugs? * How much of each study drug is in the blood at different times? * Whether the body makes antibodies against the study drugs (which could make the drugs less effective or could lead to side effects)
This description comes directly from the study's public registry record.
Clinical Trials Administrator · 844-734-6643 · clinicaltrials@regeneron.com
Always discuss trial participation with your own doctor first.
| Toronto General Hospital | Toronto, Ontario, Canada | Recruiting |
| Hospital Pablo Tobon Uribe | Medellín, Antioquia, Colombia | Recruiting |
| Semmelweis University/Semmelweis Egyetem | Budapest, Hungary | Recruiting |
| Amrita Institute of Medical Sciences (AIMS) and Research Centre Aims | Kochi, Kerala, India | Recruiting |
| K J Somaiya Super Specialty Hospital & Research Centre | Mumbai, Maharashtra, India | Recruiting |
| Rajiv Gandhi Cancer Institute & Research Center (RGCIRC) - Rohini Campus | New Delhi, National Capital Territory of Delhi, India | Recruiting |
| Postgraduate Institute of Medical Education & Research | Chandigarh, India | Recruiting |
| Bhagwan Mahaveer Cancer Hospital and Research Centre (BMCHRC) | Jaipur, India | Recruiting |
| Aou Careggi | Florence, Firenze, Italy | Recruiting |
| SC Hematology, AOU Città della Salute e della Scienza di Torino | Torino, Italy | Recruiting |
| Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital | Nagoya, Aichi-ken, Japan | Withdrawn |
| University of Tsukuba Hospital | Tsukuba, Ibaraki, Japan | Recruiting |
+ 33 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05744921