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Study identifier: NCT05738694 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neoadjuvant of Axitinib Plus PD-1 to Improve Disease Free Survival of Patients With Renal Cell Carcinoma

Condition: Renal Cell Carcinoma · Neoadjuvant  ·  Sponsor: ZHOU FANGJIAN

PhasePhase 3
Planned participants298
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The study included 298 RCC patients who were at high risk for recurrence after nephrectomy (T2G3-4 or T3-4 or N1). They were randomly divided to receive axitinib plus PD-1 + surgery or surgery alone at a ratio of 1:1, so as to determine the efficacy of the neoadjuvant combination of axitinib plus PD-1.

This description comes directly from the study's public registry record.

Talk to the study team

Zhiling Zhang, Professor  ·  +86-020-87343860  ·  zhangzhl@sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (8)

Cancer Hospital Chinese Academy of Medical SciencesBeijing, ChinaRecruiting
Peking University First HospitalBeijing, ChinaRecruiting
Sun Yat-sen University Cancer CenterGuangzhou, ChinaRecruiting
Anhui Provincial HospitalHefei, ChinaRecruiting
Fudan University Cancer HospitalShanghai, ChinaRecruiting
West China HospitalSichuan, ChinaRecruiting
Tianjin Medical University Cancer Institute and HospitalTianjin, ChinaRecruiting
The First Affiliated Hospital of Zhengzhou HospitalZhengzhou, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05738694