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Study identifier: NCT05738616 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Lenvatinib Combined With TACE and Camrelizumab in Conversion Resection for Advanced Hepatocellular Carcinoma (LEN-TAC Study)

Condition: Advanced Hepatocellular Carcinoma  ·  Sponsor: Wen Tianfu

PhasePhase 3
Planned participants196
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Compared to systemic therapy alone, conversion therapy is promising to improve the prognosis of patients with advanced hepatocellular carcinoma (HCC). Triple therapy (lenvatinib combined with transcatheter arterial chemoembolization and camrelizumab) may have significant efficacy in conversion therapy for patients with advanced HCC, but its safety and efficacy remain unknown. To address this, we have designed a randomized, open-label, parallel-controlled trial to evaluate the safety and efficacy of lenvatinib combined with transcatheter arterial chemoembolization and camrelizumab versus lenvatinib combined with transcatheter arterial chemoembolization in conversion resection for advanced HCC. Totally 196 patients with BCLC C stage HCC will be rigorously screened and included, and the primary endpoints of the study are overall survival. This study aims to provide valuable insights into new treatment strategies for advanced HCC.

This description comes directly from the study's public registry record.

Talk to the study team

Tianfu Wen, Professor  ·  86-18980601471  ·  wentianfu@scu.edu.cn

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Locations (1)

HuaXi hospitalChengdu, Sichuan, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05738616