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Study identifier: NCT05737940 Synced from ClinicalTrials.gov · July 27, 2026
● Completed

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2

Condition: Pulmonary Hypertension (World Health Organization Group 2) · Heart Failure  ·  Sponsor: AstraZeneca

PhasePhase 2
Planned participants260
Who can joinAll sexes, 18 Years to 130 Years
Healthy volunteersNo

About this study

This study is intended to assess the ability of AZD3427 to reduce pulmonary vascular resistance (PVR) after 24 weeks of treatment in participants with heart failure (HF) and pulmonary hypertension (PH) Group 2

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (60)

Research SiteBeverly Hills, California, United States
Research SiteLa Jolla, California, United States
Research SiteNew Haven, Connecticut, United States
Research SiteBaltimore, Maryland, United States
Research SiteSt Louis, Missouri, United States
Research SiteOmaha, Nebraska, United States
Research SiteRock Hill, South Carolina, United States
Research SiteLinz, Austria
Research SiteVienna, Austria
Research SiteEdmonton, Alberta, Canada
Research SiteVancouver, British Columbia, Canada
Research SiteHalifax, Nova Scotia, Canada

+ 48 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05737940