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Study identifier: NCT05736198 Synced from ClinicalTrials.gov · July 28, 2026
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Comparison of Two Sedation Regimens for Awake Fiberoptic Intubation

Condition: Awake Fiberoptic Intubation · Difficult Airway  ·  Sponsor: University of Illinois at Chicago

PhaseN/A
Planned participants96
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to examine the effects of different sedation drugs used for the awake fiberoptic intubation procedure. Benzodiazapines and narcotics (such as midazolam and fentanyl) are standard drugs used for sedation during awake fiberoptic intubation. Dexmedetomidine, midazolam, and fentanyl are approved by the Food and Drug Administration (FDA) procedural sedation. These drugs might be given to the patient regardless of their participation in the study. In addition to midazolam and fentanyl study subjects will also receive either dexmedetomidine or a placebo (a salt solution that contains no drug). It is believed that dexmedetomidine will not slow down breathing as much as the combination of the valium-like drug and narcotic. In our study, we are trying to determine if this is the best drug for sedation during an awake fiberoptic procedure.

This description comes directly from the study's public registry record.

Talk to the study team

Alexandra Barabanova, MS  ·  (312)355-5733  ·  barabano@uic.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of IllinoisChicago, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05736198