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Study identifier: NCT05731024 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Closed-loop Synchronization Versus Conventional Synchronization

Condition: Acute Respiratory Failure · Pediatric Respiratory Distress Syndrome  ·  Sponsor: Dr. Behcet Uz Children's Hospital

PhaseNA
Planned participants15
Who can joinAll sexes, 1 Month to 18 Years
Healthy volunteersNo

About this study

A prior research indicated that asynchrony between the patient and ventilator occurred in 33 percent of 19,175 breaths, and was seen in every patient. The most prevalent kind of asynchrony was ineffective triggering (68%), followed by delayed termination (19%), double triggering (4%) and premature termination (3%). Asynchrony between the patient and ventilator increased considerably with decreasing levels of peak inspiratory pressure, positive end-expiratory pressure, and set frequency.Despite this, more asynchrony categories exist, and there is no widely accepted categorization. Major asynchronies, however, include auto trigger, ineffective effort, and double trigger, while minor asynchronies include early/late cycle, trigger delay, and spontaneous breaths during a mandatory breath. This study aims to compare the safety and efficacy of a closed-loop synchronization controller with conventional control of synchronization during invasive mechanical ventilation of spontaneous breathing of pediatric patients in a pediatric intensive care unit (PICU).

This description comes directly from the study's public registry record.

Talk to the study team

Hasan Agin, Professor  ·  +905362013162  ·  hasanagin@gmail.com

Always discuss trial participation with your own doctor first.

Locations (5)

Aydin Obstetric and pediatrics HospitalAydin, Turkey (Türkiye)Recruiting
Erzurum Regional Research and Training HospitalErzurum, Turkey (Türkiye)Recruiting
Erzurum Regional Research and Training HospitalErzurum, Turkey (Türkiye)Recruiting
Cam Sakura Research and Training HospitalIstanbul, Turkey (Türkiye)Recruiting
The Health Sciences University Izmir Behçet Uz Child Health and Diseases Research and Training HospitalIzmir, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT05731024