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Study identifier: NCT05728775 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

REmimazolam vs Propofol Total Intravenous Anesthesia on Outcomes After Major Noncardiac SurgEry

Condition: Anesthesia · Surgery-Complications  ·  Sponsor: Nanfang Hospital, Southern Medical University

PhasePhase 4
Planned participants7188
Who can joinAll sexes, 45 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this randomized controlled trial is to compare total intravenous anesthesia with remimazolam vs total intravenous anesthesia with propofol in moderate-to-high risk patients undergoing major elective noncardiac surgery under general anesthesia. The primary hypothesis is that total intravenous anesthesia with remimazolam can increase days alive and out of hospital at postoperative day 30 compared with total intravenous anesthesia with propofol.

This description comes directly from the study's public registry record.

Talk to the study team

Bingcheng Zhao, MD  ·  86-13763313653  ·  zhaobch@mail2.sysu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (44)

The First Affiliated Hospital of Anhui Medical UniversityHefei, Anhui, ChinaRecruiting
Huainanchaoyang HospitalHuainan, Anhui, ChinaRecruiting
Suzhou First People's HospitalSuzhou, Anhui, ChinaRecruiting
Beijing Chaoyang Hospital, Capital Medical UniversityBeijing, Beijing Municipality, ChinaRecruiting
Xinqiao Hospital of ChongqingChongqing, Chongqing Municipality, ChinaRecruiting
The First People's Hospital of FoshanFoshan, Guangdong, ChinaRecruiting
Southern Medical University Zhujiang HospitalGuangzhou, Guangdong, ChinaRecruiting
Southern Medical University Nanfang HospitalGuangzhou, Guangdong, ChinaRecruiting
Zhongshan City People's HospitalZhongshan, Guangdong, ChinaRecruiting
The Affiliated Hospital of Guizhou Medical UniversityGuiyang, Guizhou, ChinaRecruiting
Qiandongnanzhou People's HospitalKaili, Guizhou, ChinaRecruiting
The Fourth Hospital of Hebei Medical UniversityShijiazhuang, Hebei, ChinaRecruiting

+ 32 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05728775