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Study identifier: NCT05728476 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Microinvasive Pars Plana Vitrectomy Combined ILM Peeling Versus Anti-VEGF Intravitreal Injection for Treatment-naïve Diabetic Macular Edema

Condition: Diabetic Macular Edema · Pars Plana Vitrectomy · Conbercept  ·  Sponsor: Tianjin Medical University Eye Hospital

PhaseNA
Planned participants102
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Diabetic macular edema (DME) is the main cause of vision loss in patients with diabetes. At present, anti-vascular endothelial growth factor (VEGF) intravitreal injection is the first-line therapy for DME, nevertheless, some patients do not respond well to anti-VEGF agents and often require multiple injections, which increases the psychological and economic burden of patients. Microinvasive pars plana vitrectomy (PPV) has been proven to be safe and effective for refractory DME. However, there are few studies on treatment-naïve DME. The purpose of this study is to explore whether early PPV combined with internal limiting membrane (ILM) peeling can reduce the treatment burden of DME patients, prevent vision loss, and maintain long-term stabilization of diabetic retinopathy.

This description comes directly from the study's public registry record.

Talk to the study team

Bojie Hu  ·  13612130943  ·  bhu07@tum.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Tianjin medical university eye hosipitalTianjin, Tianjin Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05728476