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Study identifier: NCT05727605 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Neurocognition After Radiotherapy in CNS- and Skull-base Tumors

Condition: Cognition · Brain Tumor · Magnetic Resonance Imaging  ·  Sponsor: Universitaire Ziekenhuizen KU Leuven

PhaseNA
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this multicenter prospective longitudinal study is to study the long-term impact of multimodal treatment (chemotherapy, radiotherapy and surgery) in adult brain and base of skull tumors on neurocognitive functioning. All included patients will complete a self-report inventory (subjective cognitive functioning, QoL, confounders), a cognitive test battery, an advanced MR at multiple timepoints. Moreover, toxicity will be scored according to the CTCAEv5.0 in these patients over time.

This description comes directly from the study's public registry record.

Talk to the study team

Laurien De Roeck, MD  ·  016 34 76 00  ·  Laurien.deroeck@uzleuven.be

Maarten Lambrecht, MD PhD  ·  016 34 76 00  ·  Maarten.lambrecht@uzleuven.be

Always discuss trial participation with your own doctor first.

Locations (3)

University Hospitals GhentGhent, BelgiumRecruiting
UZ LeuvenLeuven, BelgiumRecruiting
Gasthuis Zusters AntwerpenWilrijk, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT05727605